home *** CD-ROM | disk | FTP | other *** search
| Unknown | 1992-06-06 | 324.4 KB |
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MacOS 8.1
|
Win98
|
DOS
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| Confidence | Program | Detection | Match Type | Support
|
|---|
| 66%
| dexvert
| OS/2 Installation Package (archive/os2InstallPackage)
| ext
| Supported |
| 1%
| dexvert
| BeOS Installation Package (archive/beOSInstallPackage)
| ext
| Unsupported |
| 1%
| dexvert
| Newton Package (archive/newtonPackage)
| ext
| Unsupported |
| 1%
| dexvert
| Independence War 2 mod Package (other/independenceWar2ModPackage)
| ext
| Unsupported |
| 100%
| file
| data
| default
|
|
hex view+--------+-------------------------+-------------------------+--------+--------+
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|00000480| 2f 0d 00 00 38 31 00 00 | 00 01 7c 1e 04 00 47 0b |/...81..|..|...G.|
|00000490| 00 00 38 32 00 00 00 01 | c3 29 04 00 53 0b 00 00 |..82....|.)..S...|
|000004a0| 38 33 00 00 00 01 16 35 | 04 00 b2 0a 00 00 38 34 |83.....5|......84|
|000004b0| 00 00 00 01 c8 3f 04 00 | 92 0e 00 00 38 35 00 00 |.....?..|....85..|
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|000004d0| 58 5b 04 00 18 0c 00 00 | 38 37 00 00 00 01 70 67 |X[......|87....pg|
|000004e0| 04 00 f7 0b 00 00 38 38 | 00 00 00 01 67 73 04 00 |......88|....gs..|
|000004f0| a4 0f 00 00 38 39 00 00 | 00 01 0b 83 04 00 09 0c |....89..|........|
|00000500| 00 00 39 30 00 00 00 01 | 14 8f 04 00 32 0d 00 00 |..90....|....2...|
|00000510| 39 31 00 00 00 01 46 9c | 04 00 24 0c 00 00 39 32 |91....F.|..$...92|
|00000520| 00 00 00 01 6a a8 04 00 | 41 0b 00 00 39 33 00 00 |....j...|A...93..|
|00000530| 00 01 ab b3 04 00 c5 0b | 00 00 39 34 00 00 00 01 |........|..94....|
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|00000550| 04 00 60 0e 00 00 39 36 | 00 00 00 01 17 da 04 00 |..`...96|........|
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|00000580| 39 39 00 00 00 01 0a 06 | 05 00 79 0b 00 00 00 00 |99......|..y.....|
|00000590| 00 00 00 00 83 11 05 00 | 00 00 00 00 24 55 6e 69 |........|....$Uni|
|000005a0| 71 75 65 5f 49 44 7b 59 | 52 42 30 38 31 30 30 7d |que_ID{Y|RB08100}|
|000005b0| 0d 0a 24 54 69 74 6c 65 | 7b 43 6c 6f 6d 69 70 72 |..$Title|{Clomipr|
|000005c0| 61 6d 69 6e 65 20 54 72 | 65 61 74 6d 65 6e 74 20 |amine Tr|eatment |
|000005d0| 6f 66 20 41 67 6f 72 61 | 70 68 6f 62 69 63 20 57 |of Agora|phobic W|
|000005e0| 6f 6d 65 6e 3a 20 20 41 | 6e 20 45 69 67 68 74 2d |omen: A|n Eight-|
|000005f0| 57 65 65 6b 20 43 6f 6e | 74 72 6f 6c 6c 65 64 20 |Week Con|trolled |
|00000600| 54 72 69 61 6c 7d 0d 0a | 24 41 75 74 68 6f 72 7b |Trial}..|$Author{|
|00000610| 0d 0a 4a 6f 68 6e 73 74 | 6f 6e 2c 20 44 47 0d 0a |..Johnst|on, DG..|
|00000620| 54 72 6f 79 65 72 2c 20 | 49 45 0d 0a 57 68 69 74 |Troyer, |IE..Whit|
|00000630| 73 65 74 74 2c 20 53 46 | 7d 0d 0a 24 41 66 66 69 |sett, SF|}..$Affi|
|00000640| 6c 69 61 74 69 6f 6e 7b | 43 61 6c 67 61 72 79 20 |liation{|Calgary |
|00000650| 47 65 6e 20 48 6f 73 70 | 2c 20 55 6e 69 76 20 6f |Gen Hosp|, Univ o|
|00000660| 66 20 43 61 6c 67 61 72 | 79 2c 20 41 6c 62 65 72 |f Calgar|y, Alber|
|00000670| 74 61 20 43 68 69 6c 64 | 72 65 6e 27 73 20 48 6f |ta Child|ren's Ho|
|00000680| 73 70 20 52 65 73 65 61 | 72 63 68 20 43 74 72 2c |sp Resea|rch Ctr,|
|00000690| 20 43 61 6c 67 61 72 79 | 2c 20 41 6c 62 65 72 74 | Calgary|, Albert|
|000006a0| 61 7d 0d 0a 24 53 75 62 | 6a 65 63 74 7b 43 6c 6f |a}..$Sub|ject{Clo|
|000006b0| 6d 69 70 72 61 6d 69 6e | 65 20 69 6e 20 61 67 6f |mipramin|e in ago|
|000006c0| 72 61 70 68 6f 62 69 61 | 3b 0d 0a 41 67 6f 72 61 |raphobia|;..Agora|
|000006d0| 70 68 6f 62 69 61 20 63 | 6c 6f 6d 69 70 72 61 6d |phobia c|lomipram|
|000006e0| 69 6e 65 20 69 6e 7d 0d | 0a 24 4a 6f 75 72 6e 61 |ine in}.|.$Journa|
|000006f0| 6c 7b 41 72 63 68 20 47 | 65 6e 20 50 73 79 63 68 |l{Arch G|en Psych|
|00000700| 69 61 74 72 79 7d 0d 0a | 24 56 6f 6c 75 6d 65 7b |iatry}..|$Volume{|
|00000710| 34 35 7d 0d 0a 24 50 61 | 67 65 7b 34 35 33 2d 34 |45}..$Pa|ge{453-4|
|00000720| 35 39 7d 0d 0a 24 44 61 | 74 65 7b 4d 61 79 20 31 |59}..$Da|te{May 1|
|00000730| 39 38 38 7d 0d 0a 24 59 | 42 56 6f 6c 7b 31 39 38 |988}..$Y|BVol{198|
|00000740| 39 20 59 65 61 72 20 42 | 6f 6f 6b 20 6f 66 20 50 |9 Year B|ook of P|
|00000750| 73 79 63 68 69 61 74 72 | 79 20 61 6e 64 20 61 6e |sychiatr|y and an|
|00000760| 64 20 41 70 70 6c 69 65 | 64 20 4d 65 6e 74 61 6c |d Applie|d Mental|
|00000770| 20 48 65 61 6c 74 68 7d | 0d 0a 24 43 68 61 70 74 | Health}|..$Chapt|
|00000780| 65 72 7b 31 30 2d 35 31 | 7d 0d 0a 24 59 42 45 64 |er{10-51|}..$YBEd|
|00000790| 69 74 6f 72 7b 44 72 73 | 2e 20 54 61 6c 62 6f 74 |itor{Drs|. Talbot|
|000007a0| 74 2c 20 46 72 61 6e 63 | 65 73 2c 20 46 72 65 65 |t, Franc|es, Free|
|000007b0| 64 6d 61 6e 2c 20 4d 65 | 6c 74 7a 65 72 2c 20 53 |dman, Me|ltzer, S|
|000007c0| 63 68 6f 77 61 6c 74 65 | 72 2c 20 61 6e 64 20 57 |chowalte|r, and W|
|000007d0| 65 69 6e 65 72 7d 0d 0a | 24 54 61 62 6c 65 7b 7d |einer}..|$Table{}|
|000007e0| 0d 0a 24 43 6f 6d 6d 65 | 6e 74 61 74 6f 72 7b 44 |..$Comme|ntator{D|
|000007f0| 2e 58 2e 20 46 72 65 65 | 64 6d 61 6e 2c 20 4d 2e |.X. Free|dman, M.|
|00000800| 44 2e 7d 0d 0a 0d 0a 43 | 6f 70 79 72 69 67 68 74 |D.}....C|opyright|
|00000810| 20 28 63 29 20 59 65 61 | 72 20 42 6f 6f 6b 20 4d | (c) Yea|r Book M|
|00000820| 65 64 69 63 61 6c 20 50 | 75 62 6c 69 73 68 65 72 |edical P|ublisher|
|00000830| 73 2c 20 49 6e 63 2e 2c | 20 31 39 38 39 0d 0a 0d |s, Inc.,| 1989...|
|00000840| 0a 31 39 38 39 20 59 65 | 61 72 20 42 6f 6f 6b 20 |.1989 Ye|ar Book |
|00000850| 6f 66 20 50 73 79 63 68 | 69 61 74 72 79 20 61 6e |of Psych|iatry an|
|00000860| 64 20 41 70 70 6c 69 65 | 64 20 4d 65 6e 74 61 6c |d Applie|d Mental|
|00000870| 20 48 65 61 6c 74 68 20 | 28 52 29 0d 0a 0d 0a 43 | Health |(R)....C|
|00000880| 68 61 70 74 65 72 20 31 | 30 2d 2d 50 73 79 63 68 |hapter 1|0--Psych|
|00000890| 6f 70 68 61 72 6d 61 63 | 6f 6c 6f 67 79 0d 0a 0d |opharmac|ology...|
|000008a0| 0a 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |.-------|--------|
|000008b0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000008c0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000008d0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000008e0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000008f0| 2d 0d 0a 43 6c 6f 6d 69 | 70 72 61 6d 69 6e 65 20 |-..Clomi|pramine |
|00000900| 54 72 65 61 74 6d 65 6e | 74 20 6f 66 20 41 67 6f |Treatmen|t of Ago|
|00000910| 72 61 70 68 6f 62 69 63 | 20 57 6f 6d 65 6e 3a 20 |raphobic| Women: |
|00000920| 20 41 6e 20 45 69 67 68 | 74 2d 57 65 65 6b 20 43 | An Eigh|t-Week C|
|00000930| 6f 6e 74 72 6f 6c 6c 65 | 64 20 54 72 69 61 6c 0d |ontrolle|d Trial.|
|00000940| 0a 0d 0a 4a 6f 68 6e 73 | 74 6f 6e 20 44 47 2c 20 |...Johns|ton DG, |
|00000950| 54 72 6f 79 65 72 20 49 | 45 2c 20 57 68 69 74 73 |Troyer I|E, Whits|
|00000960| 65 74 74 20 53 46 0d 0a | 28 43 61 6c 67 61 72 79 |ett SF..|(Calgary|
|00000970| 20 47 65 6e 20 48 6f 73 | 70 2c 20 55 6e 69 76 20 | Gen Hos|p, Univ |
|00000980| 6f 66 20 43 61 6c 67 61 | 72 79 2c 20 41 6c 62 65 |of Calga|ry, Albe|
|00000990| 72 74 61 20 43 68 69 6c | 64 72 65 6e 27 73 20 48 |rta Chil|dren's H|
|000009a0| 6f 73 70 20 52 65 73 65 | 61 72 63 68 20 43 74 72 |osp Rese|arch Ctr|
|000009b0| 2c 0d 0a 43 61 6c 67 61 | 72 79 2c 20 41 6c 62 65 |,..Calga|ry, Albe|
|000009c0| 72 74 61 29 0d 0a 41 72 | 63 68 20 47 65 6e 20 50 |rta)..Ar|ch Gen P|
|000009d0| 73 79 63 68 69 61 74 72 | 79 20 34 35 3a 34 35 33 |sychiatr|y 45:453|
|000009e0| 2d 34 35 39 2c 20 4d 61 | 79 20 31 39 38 38 0d 0a |-459, Ma|y 1988..|
|000009f0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a00| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a10| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a20| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a30| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00000a40| 0d 0a 0d 0a 41 62 73 74 | 72 61 63 74 0d 0a 0d 0a |....Abst|ract....|
|00000a50| 20 20 20 20 20 54 68 65 | 20 74 72 69 63 79 63 6c | The| tricycl|
|00000a60| 69 63 20 64 72 75 67 20 | 63 6c 6f 6d 69 70 72 61 |ic drug |clomipra|
|00000a70| 6d 69 6e 65 20 77 61 73 | 20 65 76 61 6c 75 61 74 |mine was| evaluat|
|00000a80| 65 64 20 69 6e 20 61 6e | 20 38 2d 77 65 65 6b 2c |ed in an| 8-week,|
|00000a90| 0d 0a 70 6c 61 63 65 62 | 6f 2d 63 6f 6e 74 72 6f |..placeb|o-contro|
|00000aa0| 6c 6c 65 64 20 73 74 75 | 64 79 20 6f 66 20 37 30 |lled stu|dy of 70|
|00000ab0| 20 77 6f 6d 65 6e 20 6d | 65 65 74 69 6e 67 20 44 | women m|eeting D|
|00000ac0| 53 4d 2d 49 49 49 20 63 | 72 69 74 65 72 69 61 20 |SM-III c|riteria |
|00000ad0| 66 6f 72 20 61 67 6f 72 | 61 70 68 6f 62 69 61 2e |for agor|aphobia.|
|00000ae0| 0d 0a 54 68 65 20 70 61 | 74 69 65 6e 74 73 2c 20 |..The pa|tients, |
|00000af0| 61 67 65 64 20 31 38 2d | 37 30 20 79 65 61 72 73 |aged 18-|70 years|
|00000b00| 2c 20 77 65 72 65 20 64 | 72 75 67 20 66 72 65 65 |, were d|rug free|
|00000b10| 20 66 6f 72 20 61 74 20 | 6c 65 61 73 74 20 32 20 | for at |least 2 |
|00000b20| 77 65 65 6b 73 20 62 65 | 66 6f 72 65 20 74 68 65 |weeks be|fore the|
|00000b30| 0d 0a 74 72 69 61 6c 2e | 20 20 54 68 65 20 64 72 |..trial.| The dr|
|00000b40| 6f 70 6f 75 74 20 72 61 | 74 65 20 77 61 73 20 33 |opout ra|te was 3|
|00000b50| 35 25 2e 20 20 54 68 65 | 20 69 6e 69 74 69 61 6c |5%. The| initial|
|00000b60| 20 64 6f 73 65 20 6f 66 | 20 63 6c 6f 6d 69 70 72 | dose of| clomipr|
|00000b70| 61 6d 69 6e 65 20 77 61 | 73 20 32 35 20 6d 67 0d |amine wa|s 25 mg.|
|00000b80| 0a 64 61 69 6c 79 2c 20 | 61 6e 64 20 74 68 65 20 |.daily, |and the |
|00000b90| 70 65 61 6b 20 64 6f 73 | 65 20 77 61 73 20 33 30 |peak dos|e was 30|
|00000ba0| 30 20 6d 67 20 64 61 69 | 6c 79 2e 20 20 54 68 65 |0 mg dai|ly. The|
|00000bb0| 20 6d 65 61 6e 20 64 6f | 73 65 20 6f 66 20 63 6c | mean do|se of cl|
|00000bc0| 6f 6d 69 70 72 61 6d 69 | 6e 65 20 77 61 73 20 38 |omiprami|ne was 8|
|00000bd0| 33 0d 0a 6d 67 20 64 61 | 69 6c 79 2e 0d 0a 20 20 |3..mg da|ily... |
|00000be0| 20 20 20 41 73 73 65 73 | 73 6d 65 6e 74 73 20 61 | Asses|sments a|
|00000bf0| 74 20 34 20 61 6e 64 20 | 38 20 77 65 65 6b 73 20 |t 4 and |8 weeks |
|00000c00| 73 68 6f 77 65 64 20 74 | 68 61 74 20 63 6c 6f 6d |showed t|hat clom|
|00000c10| 69 70 72 61 6d 69 6e 65 | 20 77 61 73 20 73 69 67 |ipramine| was sig|
|00000c20| 6e 69 66 69 63 61 6e 74 | 6c 79 0d 0a 62 65 74 74 |nificant|ly..bett|
|00000c30| 65 72 20 74 68 61 6e 20 | 70 6c 61 63 65 62 6f 20 |er than |placebo |
|00000c40| 69 6e 20 73 65 76 65 72 | 61 6c 20 69 6e 64 69 63 |in sever|al indic|
|00000c50| 65 73 20 6f 66 20 70 68 | 6f 62 69 63 20 73 79 6d |es of ph|obic sym|
|00000c60| 70 74 6f 6d 73 20 61 6e | 64 20 6f 6e 20 6d 65 61 |ptoms an|d on mea|
|00000c70| 73 75 72 65 73 20 6f 66 | 0d 0a 64 65 70 72 65 73 |sures of|..depres|
|00000c80| 73 69 6f 6e 20 61 6e 64 | 20 64 79 73 70 68 6f 72 |sion and| dysphor|
|00000c90| 69 61 2e 20 20 49 6e 63 | 72 65 61 73 65 64 20 73 |ia. Inc|reased s|
|00000ca0| 77 65 61 74 69 6e 67 2c | 20 6d 6f 75 74 68 20 64 |weating,| mouth d|
|00000cb0| 72 79 6e 65 73 73 2c 20 | 61 6e 64 20 63 6f 6e 73 |ryness, |and cons|
|00000cc0| 74 69 70 61 74 69 6f 6e | 0d 0a 77 65 72 65 20 6d |tipation|..were m|
|00000cd0| 6f 72 65 20 66 72 65 71 | 75 65 6e 74 20 69 6e 20 |ore freq|uent in |
|00000ce0| 70 61 74 69 65 6e 74 73 | 20 67 69 76 65 6e 20 63 |patients| given c|
|00000cf0| 6c 6f 6d 69 70 72 61 6d | 69 6e 65 20 74 68 61 6e |lomipram|ine than|
|00000d00| 20 69 6e 20 70 6c 61 63 | 65 62 6f 20 72 65 63 69 | in plac|ebo reci|
|00000d10| 70 69 65 6e 74 73 2e 0d | 0a 53 65 76 65 72 61 6c |pients..|.Several|
|00000d20| 20 73 6f 6d 61 74 69 63 | 20 73 79 6d 70 74 6f 6d | somatic| symptom|
|00000d30| 73 20 61 73 73 6f 63 69 | 61 74 65 64 20 77 69 74 |s associ|ated wit|
|00000d40| 68 20 61 67 6f 72 61 70 | 68 6f 62 69 61 20 77 65 |h agorap|hobia we|
|00000d50| 72 65 20 6c 65 73 73 20 | 66 72 65 71 75 65 6e 74 |re less |frequent|
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|00002b60| 73 20 6f 66 20 6f 76 65 | 72 63 6f 6d 69 6e 67 20 |s of ove|rcoming |
|00002b70| 62 6f 74 68 20 70 68 79 | 73 69 6f 6c 6f 67 69 63 |both phy|siologic|
|00002b80| 20 61 6e 64 20 70 73 79 | 63 68 6f 6c 6f 67 69 63 | and psy|chologic|
|00002b90| 20 64 65 70 65 6e 64 65 | 6e 63 65 20 6f 6e 20 61 | depende|nce on a|
|00002ba0| 20 64 72 75 67 0d 0a 6f | 72 20 61 6c 63 6f 68 6f | drug..o|r alcoho|
|00002bb0| 6c 2e 20 20 52 65 68 61 | 62 69 6c 69 74 61 74 69 |l. Reha|bilitati|
|00002bc0| 6f 6e 20 69 73 20 74 68 | 65 20 72 65 74 75 72 6e |on is th|e return|
|00002bd0| 20 74 6f 20 6f 70 74 69 | 6d 61 6c 20 68 65 61 6c | to opti|mal heal|
|00002be0| 74 68 20 74 68 72 6f 75 | 67 68 20 6d 65 64 69 63 |th throu|gh medic|
|00002bf0| 61 6c 2c 0d 0a 70 73 79 | 63 68 6f 6c 6f 67 69 63 |al,..psy|chologic|
|00002c00| 2c 20 73 6f 63 69 61 6c | 2c 20 61 6e 64 20 70 65 |, social|, and pe|
|00002c10| 65 72 20 67 72 6f 75 70 | 20 73 75 70 70 6f 72 74 |er group| support|
|00002c20| 2e 0d 0a 0d 0a 50 6f 73 | 74 2d 43 6f 6d 6d 65 6e |.....Pos|t-Commen|
|00002c30| 74 0d 0a 0d 0a 20 20 20 | 20 20 54 68 65 20 70 72 |t.... | The pr|
|00002c40| 6f 63 65 73 73 20 6f 66 | 20 64 65 66 69 6e 69 6e |ocess of| definin|
|00002c50| 67 20 74 65 72 6d 73 20 | 69 73 20 65 73 73 65 6e |g terms |is essen|
|00002c60| 74 69 61 6c 20 74 6f 20 | 74 68 65 20 63 6c 65 61 |tial to |the clea|
|00002c70| 72 20 63 6f 6d 6d 75 6e | 69 63 61 74 69 6f 6e 20 |r commun|ication |
|00002c80| 74 68 61 74 0d 0a 69 73 | 20 6e 65 63 65 73 73 61 |that..is| necessa|
|00002c90| 72 79 20 69 6e 20 72 65 | 73 65 61 72 63 68 2c 20 |ry in re|search, |
|00002ca0| 63 6c 69 6e 69 63 61 6c | 20 64 69 73 63 6f 75 72 |clinical| discour|
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|00002cc0| 75 6c 61 74 69 6f 6e 20 | 6f 66 20 70 75 62 6c 69 |ulation |of publi|
|00002cd0| 63 0d 0a 70 6f 6c 69 63 | 79 2e 20 20 54 68 65 20 |c..polic|y. The |
|00002ce0| 65 66 66 6f 72 74 20 64 | 65 73 63 72 69 62 65 64 |effort d|escribed|
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|00002d40| 65 72 6d 73 20 61 6e 64 | 20 64 65 66 69 6e 69 74 |erms and| definit|
|00002d50| 69 6f 6e 73 20 69 6e 20 | 74 68 65 20 61 64 64 69 |ions in |the addi|
|00002d60| 63 74 69 6f 6e 73 20 61 | 6e 64 20 77 69 6c 6c 0d |ctions a|nd will.|
|00002d70| 0a 68 65 6c 70 20 66 6f | 72 6d 20 61 20 66 6f 75 |.help fo|rm a fou|
|00002d80| 6e 64 61 74 69 6f 6e 20 | 66 6f 72 20 65 73 74 61 |ndation |for esta|
|00002d90| 62 6c 69 73 68 69 6e 67 | 20 64 69 61 67 6e 6f 73 |blishing| diagnos|
|00002da0| 74 69 63 20 63 72 69 74 | 65 72 69 61 20 66 6f 72 |tic crit|eria for|
|00002db0| 20 74 68 65 73 65 0d 0a | 63 6f 6e 64 69 74 69 6f | these..|conditio|
|00002dc0| 6e 73 2e 2d 2d 41 2e 20 | 46 72 61 6e 63 65 73 2c |ns.--A. |Frances,|
|00002dd0| 20 4d 2e 44 2e 0d 0a 24 | 55 6e 69 71 75 65 5f 49 | M.D...$|Unique_I|
|00002de0| 44 7b 59 52 42 30 38 31 | 30 33 7d 0d 0a 24 54 69 |D{YRB081|03}..$Ti|
|00002df0| 74 6c 65 7b 50 65 72 73 | 70 65 63 74 69 76 65 73 |tle{Pers|pectives|
|00002e00| 20 6f 6e 20 41 64 6f 6c | 65 73 63 65 6e 74 20 53 | on Adol|escent S|
|00002e10| 75 62 73 74 61 6e 63 65 | 20 55 73 65 3a 20 20 41 |ubstance| Use: A|
|00002e20| 20 44 65 66 69 6e 65 64 | 20 50 6f 70 75 6c 61 74 | Defined| Populat|
|00002e30| 69 6f 6e 20 53 74 75 64 | 79 7d 0d 0a 24 41 75 74 |ion Stud|y}..$Aut|
|00002e40| 68 6f 72 7b 0d 0a 52 6f | 62 69 6e 73 6f 6e 2c 20 |hor{..Ro|binson, |
|00002e50| 54 4e 0d 0a 4b 69 6c 6c | 65 6e 2c 20 4a 44 0d 0a |TN..Kill|en, JD..|
|00002e60| 54 61 79 6c 6f 72 2c 20 | 43 42 0d 0a 54 65 6c 63 |Taylor, |CB..Telc|
|00002e70| 68 2c 20 4d 4a 0d 0a 42 | 72 79 73 6f 6e 2c 20 53 |h, MJ..B|ryson, S|
|00002e80| 57 0d 0a 53 61 79 6c 6f | 72 2c 20 4b 45 0d 0a 4d |W..Saylo|r, KE..M|
|00002e90| 61 72 6f 6e 2c 20 44 4a | 0d 0a 4d 61 63 63 6f 62 |aron, DJ|..Maccob|
|00002ea0| 79 2c 20 4e 0d 0a 46 61 | 72 71 75 68 61 72 2c 20 |y, N..Fa|rquhar, |
|00002eb0| 4a 57 7d 0d 0a 24 41 66 | 66 69 6c 69 61 74 69 6f |JW}..$Af|filiatio|
|00002ec0| 6e 7b 53 74 61 6e 66 6f | 72 64 20 55 6e 69 76 7d |n{Stanfo|rd Univ}|
|00002ed0| 0d 0a 24 53 75 62 6a 65 | 63 74 7b 53 75 62 73 74 |..$Subje|ct{Subst|
|00002ee0| 61 6e 63 65 20 75 73 65 | 20 61 64 6f 6c 65 73 63 |ance use| adolesc|
|00002ef0| 65 6e 74 2c 20 70 65 72 | 73 70 65 63 74 69 76 65 |ent, per|spective|
|00002f00| 73 20 6f 6e 3b 0d 0a 41 | 64 6f 6c 65 73 63 65 6e |s on;..A|dolescen|
|00002f10| 74 20 73 75 62 73 74 61 | 6e 63 65 20 75 73 65 2c |t substa|nce use,|
|00002f20| 20 70 65 72 73 70 65 63 | 74 69 76 65 73 20 6f 6e | perspec|tives on|
|00002f30| 7d 0d 0a 24 4a 6f 75 72 | 6e 61 6c 7b 4a 41 4d 41 |}..$Jour|nal{JAMA|
|00002f40| 7d 0d 0a 24 56 6f 6c 75 | 6d 65 7b 32 35 38 7d 0d |}..$Volu|me{258}.|
|00002f50| 0a 24 50 61 67 65 7b 32 | 30 37 32 2d 32 30 37 36 |.$Page{2|072-2076|
|00002f60| 7d 0d 0a 24 44 61 74 65 | 7b 4f 63 74 20 31 36 2c |}..$Date|{Oct 16,|
|00002f70| 20 31 39 38 37 7d 0d 0a | 24 59 42 56 6f 6c 7b 31 | 1987}..|$YBVol{1|
|00002f80| 39 38 39 20 59 65 61 72 | 20 42 6f 6f 6b 20 6f 66 |989 Year| Book of|
|00002f90| 20 50 73 79 63 68 69 61 | 74 72 79 20 61 6e 64 20 | Psychia|try and |
|00002fa0| 61 6e 64 20 41 70 70 6c | 69 65 64 20 4d 65 6e 74 |and Appl|ied Ment|
|00002fb0| 61 6c 20 48 65 61 6c 74 | 68 7d 0d 0a 24 43 68 61 |al Healt|h}..$Cha|
|00002fc0| 70 74 65 72 7b 31 31 2d | 33 7d 0d 0a 24 59 42 45 |pter{11-|3}..$YBE|
|00002fd0| 64 69 74 6f 72 7b 44 72 | 73 2e 20 54 61 6c 62 6f |ditor{Dr|s. Talbo|
|00002fe0| 74 74 2c 20 46 72 61 6e | 63 65 73 2c 20 46 72 65 |tt, Fran|ces, Fre|
|00002ff0| 65 64 6d 61 6e 2c 20 4d | 65 6c 74 7a 65 72 2c 20 |edman, M|eltzer, |
|00003000| 53 63 68 6f 77 61 6c 74 | 65 72 2c 20 61 6e 64 20 |Schowalt|er, and |
|00003010| 57 65 69 6e 65 72 7d 0d | 0a 24 54 61 62 6c 65 7b |Weiner}.|.$Table{|
|00003020| 54 61 62 6c 65 20 4f 6d | 69 74 74 65 64 7d 0d 0a |Table Om|itted}..|
|00003030| 24 43 6f 6d 6d 65 6e 74 | 61 74 6f 72 7b 41 2e 20 |$Comment|ator{A. |
|00003040| 46 72 61 6e 63 65 73 2c | 20 4d 2e 44 2e 7d 0d 0a |Frances,| M.D.}..|
|00003050| 0d 0a 43 6f 70 79 72 69 | 67 68 74 20 28 63 29 20 |..Copyri|ght (c) |
|00003060| 59 65 61 72 20 42 6f 6f | 6b 20 4d 65 64 69 63 61 |Year Boo|k Medica|
|00003070| 6c 20 50 75 62 6c 69 73 | 68 65 72 73 2c 20 49 6e |l Publis|hers, In|
|00003080| 63 2e 2c 20 31 39 38 39 | 0d 0a 0d 0a 31 39 38 39 |c., 1989|....1989|
|00003090| 20 59 65 61 72 20 42 6f | 6f 6b 20 6f 66 20 50 73 | Year Bo|ok of Ps|
|000030a0| 79 63 68 69 61 74 72 79 | 20 61 6e 64 20 41 70 70 |ychiatry| and App|
|000030b0| 6c 69 65 64 20 4d 65 6e | 74 61 6c 20 48 65 61 6c |lied Men|tal Heal|
|000030c0| 74 68 20 28 52 29 0d 0a | 0d 0a 43 68 61 70 74 65 |th (R)..|..Chapte|
|000030d0| 72 20 31 31 2d 2d 41 6c | 63 6f 68 6f 6c 20 61 6e |r 11--Al|cohol an|
|000030e0| 64 20 44 72 75 67 20 41 | 62 75 73 65 0d 0a 0d 0a |d Drug A|buse....|
|000030f0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003100| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003110| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003120| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003130| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003140| 0d 0a 50 65 72 73 70 65 | 63 74 69 76 65 73 20 6f |..Perspe|ctives o|
|00003150| 6e 20 41 64 6f 6c 65 73 | 63 65 6e 74 20 53 75 62 |n Adoles|cent Sub|
|00003160| 73 74 61 6e 63 65 20 55 | 73 65 3a 20 20 41 20 44 |stance U|se: A D|
|00003170| 65 66 69 6e 65 64 20 50 | 6f 70 75 6c 61 74 69 6f |efined P|opulatio|
|00003180| 6e 20 53 74 75 64 79 0d | 0a 0d 0a 52 6f 62 69 6e |n Study.|...Robin|
|00003190| 73 6f 6e 20 54 4e 2c 20 | 4b 69 6c 6c 65 6e 20 4a |son TN, |Killen J|
|000031a0| 44 2c 20 54 61 79 6c 6f | 72 20 43 42 2c 20 54 65 |D, Taylo|r CB, Te|
|000031b0| 6c 63 68 20 4d 4a 2c 20 | 42 72 79 73 6f 6e 20 53 |lch MJ, |Bryson S|
|000031c0| 57 2c 20 53 61 79 6c 6f | 72 20 4b 45 2c 20 4d 61 |W, Saylo|r KE, Ma|
|000031d0| 72 6f 6e 20 44 4a 2c 0d | 0a 4d 61 63 63 6f 62 79 |ron DJ,.|.Maccoby|
|000031e0| 20 4e 2c 20 46 61 72 71 | 75 68 61 72 20 4a 57 0d | N, Farq|uhar JW.|
|000031f0| 0a 28 53 74 61 6e 66 6f | 72 64 20 55 6e 69 76 29 |.(Stanfo|rd Univ)|
|00003200| 0d 0a 4a 41 4d 41 20 32 | 35 38 3a 32 30 37 32 2d |..JAMA 2|58:2072-|
|00003210| 32 30 37 36 2c 20 4f 63 | 74 20 31 36 2c 20 31 39 |2076, Oc|t 16, 19|
|00003220| 38 37 0d 0a 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |87..----|--------|
|00003230| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003240| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003250| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003260| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003270| 2d 2d 2d 2d 0d 0a 0d 0a | 41 62 73 74 72 61 63 74 |----....|Abstract|
|00003280| 0d 0a 0d 0a 20 20 20 20 | 20 54 68 65 20 64 65 63 |.... | The dec|
|00003290| 6c 69 6e 65 20 69 6e 20 | 64 72 75 67 20 75 73 65 |line in |drug use|
|000032a0| 20 62 79 20 61 64 6f 6c | 65 73 63 65 6e 74 73 20 | by adol|escents |
|000032b0| 74 68 61 74 20 62 65 67 | 61 6e 20 69 6e 20 31 39 |that beg|an in 19|
|000032c0| 38 30 20 6d 61 79 20 68 | 61 76 65 20 63 65 61 73 |80 may h|ave ceas|
|000032d0| 65 64 2e 0d 0a 54 68 65 | 20 61 75 74 68 6f 72 73 |ed...The| authors|
|000032e0| 20 73 75 72 76 65 79 65 | 64 20 31 2c 34 34 37 20 | surveye|d 1,447 |
|000032f0| 74 65 6e 74 68 20 67 72 | 61 64 65 20 73 74 75 64 |tenth gr|ade stud|
|00003300| 65 6e 74 73 20 69 6e 20 | 34 20 6e 6f 72 74 68 65 |ents in |4 northe|
|00003310| 72 6e 20 43 61 6c 69 66 | 6f 72 6e 69 61 20 68 69 |rn Calif|ornia hi|
|00003320| 67 68 0d 0a 73 63 68 6f | 6f 6c 73 20 74 6f 20 64 |gh..scho|ols to d|
|00003330| 69 73 63 65 72 6e 20 70 | 61 74 74 65 72 6e 73 20 |iscern p|atterns |
|00003340| 6f 66 20 64 72 75 67 20 | 75 73 65 20 61 6e 64 20 |of drug |use and |
|00003350| 74 68 65 20 65 66 66 65 | 63 74 73 20 6f 66 20 73 |the effe|cts of s|
|00003360| 6f 63 69 61 6c 20 66 61 | 63 74 6f 72 73 20 6f 6e |ocial fa|ctors on|
|00003370| 0d 0a 74 68 69 73 20 70 | 72 61 63 74 69 63 65 2e |..this p|ractice.|
|00003380| 20 20 52 65 73 70 6f 6e | 73 65 20 72 61 74 65 73 | Respon|se rates|
|00003390| 20 66 6f 72 20 74 68 65 | 20 76 61 72 69 6f 75 73 | for the| various|
|000033a0| 20 73 75 62 73 74 61 6e | 63 65 20 75 73 65 20 69 | substan|ce use i|
|000033b0| 74 65 6d 73 20 72 61 6e | 67 65 64 20 66 72 6f 6d |tems ran|ged from|
|000033c0| 0d 0a 39 30 25 20 74 6f | 20 39 32 25 2e 0d 0a 20 |..90% to| 92%... |
|000033d0| 20 20 20 20 41 6c 63 6f | 68 6f 6c 20 77 61 73 20 | Alco|hol was |
|000033e0| 74 68 65 20 73 75 62 73 | 74 61 6e 63 65 20 6d 6f |the subs|tance mo|
|000033f0| 73 74 20 6f 66 74 65 6e | 20 75 73 65 64 20 28 74 |st often| used (t|
|00003400| 61 62 6c 65 29 2e 20 20 | 4c 65 76 65 6c 73 20 6f |able). |Levels o|
|00003410| 66 20 73 75 62 73 74 61 | 6e 63 65 20 75 73 65 0d |f substa|nce use.|
|00003420| 0a 77 65 72 65 20 73 69 | 6d 69 6c 61 72 20 66 6f |.were si|milar fo|
|00003430| 72 20 62 6f 79 73 20 61 | 6e 64 20 67 69 72 6c 73 |r boys a|nd girls|
|00003440| 2e 20 20 41 6d 6f 6e 67 | 20 73 75 62 6a 65 63 74 |. Among| subject|
|00003450| 73 20 77 68 6f 20 75 73 | 65 64 20 31 20 6f 72 20 |s who us|ed 1 or |
|00003460| 6d 6f 72 65 20 73 75 62 | 73 74 61 6e 63 65 73 0d |more sub|stances.|
|00003470| 0a 6f 6e 20 61 20 64 61 | 69 6c 79 20 62 61 73 69 |.on a da|ily basi|
|00003480| 73 2c 20 37 31 25 20 73 | 6d 6f 6b 65 64 20 74 6f |s, 71% s|moked to|
|00003490| 62 61 63 63 6f 20 63 69 | 67 61 72 65 74 74 65 73 |bacco ci|garettes|
|000034a0| 2c 20 32 30 25 20 73 6d | 6f 6b 65 64 20 6d 61 72 |, 20% sm|oked mar|
|000034b0| 69 6a 75 61 6e 61 2c 20 | 61 6e 64 20 37 25 0d 0a |ijuana, |and 7%..|
|000034c0| 64 72 61 6e 6b 20 61 6c | 63 6f 68 6f 6c 2e 0d 0a |drank al|cohol...|
|000034d0| 20 20 20 20 20 55 73 65 | 20 6f 66 20 6d 61 72 69 | Use| of mari|
|000034e0| 6a 75 61 6e 61 20 62 79 | 20 66 72 69 65 6e 64 73 |juana by| friends|
|000034f0| 20 77 61 73 20 61 20 70 | 6f 77 65 72 66 75 6c 20 | was a p|owerful |
|00003500| 70 72 65 64 69 63 74 6f | 72 20 6f 66 20 61 6e 20 |predicto|r of an |
|00003510| 69 6e 63 72 65 61 73 65 | 64 20 6c 65 76 65 6c 0d |increase|d level.|
|00003520| 0a 6f 66 20 73 75 62 73 | 74 61 6e 63 65 20 75 73 |.of subs|tance us|
|00003530| 65 20 62 79 20 62 6f 74 | 68 20 62 6f 79 73 20 61 |e by bot|h boys a|
|00003540| 6e 64 20 67 69 72 6c 73 | 2e 20 20 54 68 65 20 6e |nd girls|. The n|
|00003550| 65 78 74 20 6d 6f 73 74 | 20 69 6d 70 6f 72 74 61 |ext most| importa|
|00003560| 6e 74 20 66 61 63 74 6f | 72 20 66 6f 72 0d 0a 62 |nt facto|r for..b|
|00003570| 6f 79 73 20 77 61 73 20 | 74 68 65 20 70 65 72 63 |oys was |the perc|
|00003580| 65 69 76 65 64 20 73 61 | 66 65 74 79 20 6f 66 20 |eived sa|fety of |
|00003590| 63 69 67 61 72 65 74 74 | 65 20 73 6d 6f 6b 69 6e |cigarett|e smokin|
|000035a0| 67 3b 20 66 6f 72 20 67 | 69 72 6c 73 20 74 68 65 |g; for g|irls the|
|000035b0| 20 6e 65 78 74 20 6d 6f | 73 74 0d 0a 69 6d 70 6f | next mo|st..impo|
|000035c0| 72 74 61 6e 74 20 66 61 | 63 74 6f 72 20 77 61 73 |rtant fa|ctor was|
|000035d0| 20 70 6f 6f 72 20 73 63 | 68 6f 6f 6c 20 70 65 72 | poor sc|hool per|
|000035e0| 66 6f 72 6d 61 6e 63 65 | 2e 20 20 53 69 6d 69 6c |formance|. Simil|
|000035f0| 61 72 20 66 61 63 74 6f | 72 73 20 61 63 63 6f 75 |ar facto|rs accou|
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|00003ab0| 63 74 2c 20 74 68 65 20 | 22 77 61 72 20 6f 6e 20 |ct, the |"war on |
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|00003ae0| 2e 2d 2d 41 2e 20 46 72 | 61 6e 63 65 73 2c 20 4d |.--A. Fr|ances, M|
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|00003b50| 48 61 61 73 74 72 75 70 | 2c 20 53 0d 0a 4a 65 70 |Haastrup|, S..Jep|
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|00003bb0| 73 2c 20 79 6f 75 6e 67 | 2c 20 66 6f 6c 6c 6f 77 |s, young|, follow|
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|00003c00| 74 72 20 53 63 61 6e 64 | 7d 0d 0a 24 56 6f 6c 75 |tr Scand|}..$Volu|
|00003c10| 6d 65 7b 37 37 7d 0d 0a | 24 50 61 67 65 7b 32 32 |me{77}..|$Page{22|
|00003c20| 2d 32 36 7d 0d 0a 24 44 | 61 74 65 7b 4a 61 6e 75 |-26}..$D|ate{Janu|
|00003c30| 61 72 79 20 31 39 38 38 | 7d 0d 0a 24 59 42 56 6f |ary 1988|}..$YBVo|
|00003c40| 6c 7b 31 39 38 39 20 59 | 65 61 72 20 42 6f 6f 6b |l{1989 Y|ear Book|
|00003c50| 20 6f 66 20 50 73 79 63 | 68 69 61 74 72 79 20 61 | of Psyc|hiatry a|
|00003c60| 6e 64 20 61 6e 64 20 41 | 70 70 6c 69 65 64 20 4d |nd and A|pplied M|
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|00003c80| 43 68 61 70 74 65 72 7b | 31 31 2d 34 7d 0d 0a 24 |Chapter{|11-4}..$|
|00003c90| 59 42 45 64 69 74 6f 72 | 7b 44 72 73 2e 20 54 61 |YBEditor|{Drs. Ta|
|00003ca0| 6c 62 6f 74 74 2c 20 46 | 72 61 6e 63 65 73 2c 20 |lbott, F|rances, |
|00003cb0| 46 72 65 65 64 6d 61 6e | 2c 20 4d 65 6c 74 7a 65 |Freedman|, Meltze|
|00003cc0| 72 2c 20 53 63 68 6f 77 | 61 6c 74 65 72 2c 20 61 |r, Schow|alter, a|
|00003cd0| 6e 64 20 57 65 69 6e 65 | 72 7d 0d 0a 24 54 61 62 |nd Weine|r}..$Tab|
|00003ce0| 6c 65 7b 7d 0d 0a 24 43 | 6f 6d 6d 65 6e 74 61 74 |le{}..$C|ommentat|
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|00003d00| 2e 44 2e 7d 0d 0a 0d 0a | 43 6f 70 79 72 69 67 68 |.D.}....|Copyrigh|
|00003d10| 74 20 28 63 29 20 59 65 | 61 72 20 42 6f 6f 6b 20 |t (c) Ye|ar Book |
|00003d20| 4d 65 64 69 63 61 6c 20 | 50 75 62 6c 69 73 68 65 |Medical |Publishe|
|00003d30| 72 73 2c 20 49 6e 63 2e | 2c 20 31 39 38 39 0d 0a |rs, Inc.|, 1989..|
|00003d40| 0d 0a 31 39 38 39 20 59 | 65 61 72 20 42 6f 6f 6b |..1989 Y|ear Book|
|00003d50| 20 6f 66 20 50 73 79 63 | 68 69 61 74 72 79 20 61 | of Psyc|hiatry a|
|00003d60| 6e 64 20 41 70 70 6c 69 | 65 64 20 4d 65 6e 74 61 |nd Appli|ed Menta|
|00003d70| 6c 20 48 65 61 6c 74 68 | 20 28 52 29 0d 0a 0d 0a |l Health| (R)....|
|00003d80| 43 68 61 70 74 65 72 20 | 31 31 2d 2d 41 6c 63 6f |Chapter |11--Alco|
|00003d90| 68 6f 6c 20 61 6e 64 20 | 44 72 75 67 20 41 62 75 |hol and |Drug Abu|
|00003da0| 73 65 0d 0a 0d 0a 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |se....--|--------|
|00003db0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003dc0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003dd0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003de0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003df0| 2d 2d 2d 2d 2d 2d 0d 0a | 45 6c 65 76 65 6e 20 59 |------..|Eleven Y|
|00003e00| 65 61 72 20 46 6f 6c 6c | 6f 77 2d 75 70 20 6f 66 |ear Foll|ow-up of|
|00003e10| 20 33 30 30 20 59 6f 75 | 6e 67 20 4f 70 69 6f 69 | 300 You|ng Opioi|
|00003e20| 64 20 41 64 64 69 63 74 | 73 0d 0a 0d 0a 48 61 61 |d Addict|s....Haa|
|00003e30| 73 74 72 75 70 20 53 2c | 20 4a 65 70 73 65 6e 20 |strup S,| Jepsen |
|00003e40| 50 57 0d 0a 28 4e 6f 72 | 64 76 61 6e 67 20 48 6f |PW..(Nor|dvang Ho|
|00003e50| 73 70 2c 20 47 6c 6f 73 | 74 72 75 70 2c 20 44 65 |sp, Glos|trup, De|
|00003e60| 6e 6d 61 72 6b 29 0d 0a | 41 63 74 61 20 50 73 79 |nmark)..|Acta Psy|
|00003e70| 63 68 69 61 74 72 20 53 | 63 61 6e 64 20 37 37 3a |chiatr S|cand 77:|
|00003e80| 32 32 2d 32 36 2c 20 4a | 61 6e 75 61 72 79 20 31 |22-26, J|anuary 1|
|00003e90| 39 38 38 0d 0a 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |988..---|--------|
|00003ea0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003eb0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003ec0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003ed0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003ee0| 2d 2d 2d 2d 2d 0d 0a 0d | 0a 41 62 73 74 72 61 63 |-----...|.Abstrac|
|00003ef0| 74 0d 0a 0d 0a 20 20 20 | 20 20 46 6f 72 6d 65 72 |t.... | Former|
|00003f00| 6c 79 20 6e 61 72 63 6f | 74 69 63 20 61 64 64 69 |ly narco|tic addi|
|00003f10| 63 74 69 6f 6e 20 77 61 | 73 20 63 6f 6e 73 69 64 |ction wa|s consid|
|00003f20| 65 72 65 64 20 61 20 76 | 65 72 79 20 72 65 73 69 |ered a v|ery resi|
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|00003f50| 66 6f 72 20 6d 6f 72 65 | 20 72 65 63 65 6e 74 20 |for more| recent |
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|00003f70| 69 63 74 73 20 73 65 65 | 6d 73 20 74 6f 20 62 65 |icts see|ms to be|
|00003f80| 20 66 61 72 20 62 65 74 | 74 65 72 2e 20 20 54 68 | far bet|ter. Th|
|00003f90| 72 65 65 0d 0a 68 75 6e | 64 72 65 64 20 79 6f 75 |ree..hun|dred you|
|00003fa0| 6e 67 20 6f 70 69 6f 69 | 64 20 61 64 64 69 63 74 |ng opioi|d addict|
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|00003fc0| 20 74 72 65 61 74 6d 65 | 6e 74 20 75 6e 69 74 20 | treatme|nt unit |
|00003fd0| 69 6e 20 43 6f 70 65 6e | 68 61 67 65 6e 20 69 6e |in Copen|hagen in|
|00003fe0| 20 31 39 37 33 0d 0a 77 | 65 72 65 20 66 6f 6c 6c | 1973..w|ere foll|
|00003ff0| 6f 77 65 64 20 75 70 20 | 66 6f 72 20 37 20 79 65 |owed up |for 7 ye|
|00004000| 61 72 73 2e 20 20 53 75 | 62 6a 65 63 74 73 20 61 |ars. Su|bjects a|
|00004010| 62 75 73 65 64 20 6f 70 | 69 61 74 65 73 20 64 61 |bused op|iates da|
|00004020| 69 6c 79 20 61 6e 64 20 | 69 6e 74 72 61 76 65 6e |ily and |intraven|
|00004030| 6f 75 73 6c 79 0d 0a 61 | 74 20 61 67 65 20 33 30 |ously..a|t age 30|
|00004040| 20 79 65 61 72 73 20 6f | 72 20 79 6f 75 6e 67 65 | years o|r younge|
|00004050| 72 2e 20 20 54 77 6f 20 | 68 75 6e 64 72 65 64 20 |r. Two |hundred |
|00004060| 74 68 72 65 65 20 73 75 | 62 6a 65 63 74 73 20 77 |three su|bjects w|
|00004070| 65 72 65 20 6d 61 6c 65 | 2e 20 20 4d 65 61 6e 20 |ere male|. Mean |
|00004080| 61 67 65 20 61 74 0d 0a | 6f 6e 73 65 74 20 6f 66 |age at..|onset of|
|00004090| 20 61 64 64 69 63 74 69 | 6f 6e 20 77 61 73 20 31 | addicti|on was 1|
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|000040d0| 25 20 6f 66 20 74 68 65 | 0d 0a 33 30 30 20 61 62 |% of the|..300 ab|
|000040e0| 75 73 65 64 20 73 75 62 | 73 74 61 6e 63 65 73 20 |used sub|stances |
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|00004140| 74 77 6f 20 74 68 69 72 | 64 73 20 77 65 72 65 20 |two thir|ds were |
|00004150| 6f 70 69 6f 69 64 20 61 | 64 64 69 63 74 73 2e 0d |opioid a|ddicts..|
|00004160| 0a 20 20 20 20 20 4d 6f | 72 74 61 6c 69 74 79 20 |. Mo|rtality |
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|00004300| 62 65 63 61 75 73 65 20 | 74 68 65 79 20 61 63 68 |because |they ach|
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